ying_yu@fudan.edu.cn

摘要

研究方向: 从事药物基因组学、精准医学、生物信息学等方面的研究工作。目前的主要研究方向为：利用高通量测序技术和生物信息学等手段，研究1）肿瘤发生和发展的分子机制；2）肿瘤个体化精准用药。

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1. Wang J#, Yu Y#, Shen H, Qing T, Zheng Y, Li Q, Wang S, Li N, Chai R, Xu B, Liu M, Brindley JP, McManus PD, Shi L, Hu W*. Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating pairing/reproductive development in Schistosoma japonicum. Nature Communications, 8:14693 (2017).

2. Zhang W#, Yu Y#, Hertwig F#, Thierry-Mieg J#, Zhang W#, Thierry-Mieg D, Wang J, Furlanello C, Devanarayan V, Cheng J, Deng Y, Hero B, Hong H, Jia M, Li L, Lin SM, Nikolsky Y, Oberthuer A, Qing T, Su Z, …, Shi L*, Peng Z*, Fischer M*. Comparison of RNA-seq and microarray-based models for clinical endpoint prediction. Genome Biology, 25;16:133 (2015).

3. Yu Y#, Fuscoe JC#, Zhao C, Guo G, Jia M, Qing T, Bannon DI, Lancashire L, Bao W, Du T, Luo H, Su Z, Jones WD, Moland CL, Branham WS, Qian F, Ning B, Li Y, Hong H, Guo L, Mei N, …, Shi L*, Wang C*.  A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. Nature Communications, 5, 3230 (2014).

4. Yu Y, Zhao C, Su Z, Wang C, Fuscoe JC, Tong W, Shi L*.Comprehensive RNA-Seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats. Scientific Data, 1:140013. (2014).

5. Su Z#, Łabaj PP#, Li S#, Thierry-Mieg J#, Thierry-Mieg D#, Shi W#, Wang C, Schroth GP, Setterquist RA, Thompson JF, Jones WD, Xiao W, Xu W, ,…, Yu Y, …, Kreil DP*, Mason CE*, Shi L*. A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. Nature Biotechnology, 32(9):903-14 (2014).

6. Munro SA*, Lund SP, Pine PS, Binder H, Clevert DA, Conesa A, Dopazo J, Fasold M, Hochreiter S, Hong H, Jafari N, Kreil DP, Labaj PP, Li S, Liao Y, Lin SM, Meehan J, Mason CE, Santoyo-Lopez J, Setterquist RA, Shi L,…, Yu Y, Salit M*. Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures. Nature Communications, 25;5:5125 (2014).