摘要

研究方向:  肿瘤分子流行病学: 针对肺癌、脑胶质瘤等恶性肿瘤的发生发展和治疗进行大样本和多中心的肿瘤分子流行病学研究，筛选和鉴定遗传易感基因、治疗和预后相关基因，并进行功能研究，对于恶性肿瘤的预防和个性化治疗具有重要意义。
其他兴趣方向：糖尿病分子遗传学，基因检测和操作技术。

曾经获得国家技术发明二等奖（第二完成人，1997）、国家自然科学二等奖（2007，第三完成人），省部级科技一等奖5项，获得国家级教学成果二等奖1项, 指导获得4届全国大学生挑战杯最高奖。此外, 获得全国优秀博士论文、全国优秀教师、中国青年科技奖、国家百千万人才工程国家级人选等。

1. Lu J, Zhang S, Chen D, Wang H, Wu W, Wang X, Lei Y, Wang J, Qian J, Fan W, Hu Z, Jin L, Shen H, Huang W, Wei Q, Lu D*. (2009)Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. FASEB J. Jun 22.

2. Wu W, Zhang W, Qiao R, Chen D, Wang H, Wang Y, Zhang S, Gao G, Gu A, Shen J, Qian J, Fan W, Jin L, Han B*, Lu D*. (2009)Association of XPD polymorphisms with severe toxicity in non-small cell lung cancer patients in a Chinese population. Clin Cancer Res. Jun 1;15(11):3889-95. 

3. Chen D, Tian T, Wang H, Liu H, Hu Z, Wang Y, Liu Y, Ma H, Fan W, Miao R, Sun W, Wang Y, Qian J, Jin L, Wei Q, Shen H, Huang W*, Lu D*.(2009) Association of human aryl hydrocarbon receptor gene polymorphisms with risk of lung cancer among cigarette smokers in a Chinese population. Pharmacogenet Genomics. Jan;19(1):25-34.

4. Wang H, Jin G, Wang H, Liu G, Qian J, Jin L, Wei Q, Shen H, Huang W*, Lu D*.(2009) Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export. Cancer. Feb 1;115(3):595-607.

5. Liu, Y.; Zhou, K.; Zhang, H.; Shugart, Y. Y.; Chen, L.; Xu, Z.; Zhong, Y.; Liu, H.; Jin, L.; Wei, Q.; Huang, F.; Lu, D.*; Zhou, L.*, (2008) Polymorphisms of LIG4 and XRCC4 involved in the NHEJ pathway interact to modify risk of glioma. Hum Mutat. 29, (3), 381-9.

6. Liu, Y.; Zhang, H.; Zhou, K.; Chen, L.; Xu, Z.; Zhong, Y.; Liu, H.; Li, R.; Shugart, Y. Y.; Wei, Q.; Jin, L.; Huang, F.*; Lu, D.*; Zhou, L.,(2007) Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma. Carcinogenesis. 28, (9), 1906-13.