andresruiz@fudan.edu.cn

摘要

Andres Ruiz-Linares has been working for a number of years on the genetics of populations from Latin America, including evolutionary analyses as well as gene mapping studies. His work has sought to exploit the advantages of the region for the study of human and population genetic questions of broad scientific relevance. Of special interest to this proposal the history of extensive intercontinental admixture in the region implies that the population of Latin America represents a highly informative “natural experiment” in which to analyse the role of genetic factors in phenotypic diversity, particularly for traits differentiated between Africans, Europeans and Native Americans.

He received his bachelor's degree in medicine from the university of Rosario in 1984, his master's degree in biochemistry from the university of Paris vii in 1987, and his doctor's degree in genetics from the university of Cambridge in 1991.

1992 - postdoctoral research at Stanford university school of medicine,

1994-1998 - assistant professor of department of biochemistry at Medellin Colombia university school of medicine

1998-2000 - lecturer at British imperial college, London school of medicine

2000-2006 - lecturer, senior lecturer at British department of biology at university college London (Galton laboratory)

2006-2017 - professor, honorary professor at British genetic evolution at university college London, department of environment

2017-prensent – Professor at Fudan University, School of life sciences.

Andres Ruiz-Linares has been working for a number of years on the genetics of populations from Latin America, including evolutionary analyses as well as gene mapping studies. His work has sought to exploit the advantages of the region for the study of human and population genetic questions of broad scientific relevance. Of special interest to this proposal the history of extensive intercontinental admixture in the region implies that the population of Latin America represents a highly informative “natural experiment” in which to analyse the role of genetic factors in phenotypic diversity, particularly for traits differentiated between Africans, Europeans and Native Americans.

1986-1988. CESTA fellow of the French Ministry of Research.  

1988-1991. Overseas Research Student (ORS) Award from the Vice-Chancellors and Principals of the Universities of the United Kingdom.     

1993. Genetics Society of America award.

1995. Ciba (now Novartis) Foundation Fellow.

2002. Young Investigator Award. The National Alliance for Research on Schizophrenia and Depression (USA).

2002-2005. Editorial board member. Annals of Human Genetics.

2005-2007. Senior Editor. Annals of Human Genetics.

2008-2015. Editor in Chief. Annals of Human Genetics.

2014-2016. Nominations Committee member. American Society of Human Genetics.

1. Adhikari K, Chacon-Duque, Mendoza-Revilla J., Fuentes-Guajardo M., Ruiz-Linares A. (2017) The Genetic Diversity of the Americas. Annual Review of Genomics & Human Genetics. 18:277–96.

2. Adhikari K, Mendoza-Revilla J, Chacon-Duque JC, Fuentes-Guajardo M & Ruiz-Linares A (2016) Admixture in Latin America. Current opinion in genetics & development 41:106-114.

3. Adhikari K, Fuentes-Guajardo M, Quinto-Sanchez M, Mendoza-Revilla J, Camilo Chacon-Duque J, Acuna-Alonzo V, Jaramillo C, Arias W, Lozano RB, Perez GM, Gomez-Valdes J, Villamil-Ramirez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Cheeseman M, Rosique J, Bedoya G, Rothhammer F, Headon D, Gonzalez-Jose R, Balding D & Ruiz-Linares A (2016) A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. Nat Commun 7:11616.

4. Adhikari K, Fontanil T, Cal S, Mendoza-Revilla J, Fuentes-Guajardo M, Chacon-Duque JC, Al-Saadi F, Johansson JA, Quinto-Sanchez M, Acuna-Alonzo V, Jaramillo C, Arias W, Barquera Lozano R, Macin Perez G, Gomez-Valdes J, Villamil-Ramirez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Gonzalez-Jose R, Headon D, Lopez-Otin C, Tobin DJ, Balding D & Ruiz-Linares A (2016) A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Nat Commun 7:10815.

5. Adhikari K, Reales G, Smith AJ, Konka E, Palmen J, Quinto-Sanchez M, Acuna-Alonzo V, Jaramillo C, Arias W, Fuentes M, Pizarro M, Barquera Lozano R, Macin Perez G, Gomez-Valdes J, Villamil-Ramirez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Calderon R, Rosique J, Cheeseman M, Bhutta MF, Humphries SE, Gonzalez-Jose R, Headon D, Balding D & Ruiz-Linares A (2015) A genome-wide association study identifies multiple loci for variation in human ear morphology. Nat Commun 6:7500.

6. Ruiz-Linares A, Adhikari K, Acuna-Alonzo V, Quinto-Sanchez M, Jaramillo C, Arias W, Fuentes M, Pizarro M, Everardo P, de Avila F, Gomez-Valdes J, Leon-Mimila P, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Burley MW, Konca E, de Oliveira MZ, Veronez MR, Rubio-Codina M, Attanasio O, Gibbon S, Ray N, Gallo C, Poletti G, Rosique J, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Balding D & Gonzalez-Jose R (2014) Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals. PLoS Genet 10(9):e1004572.

7. Ruiz-Linares A (2014) How genes have illuminated the history of early Americans and Latino Americans. Cold Spring Harb Perspect Biol 7(6).