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01关于本系
Position :
本系简介

Feng Zhang

职称Professor
电话

021-31246627

地址E601-9. School of Life Sciences Building
摘要Human genomic rearrangements; copy number variations (CNVs)/structural variations (SVs) and their roles in human diseases, e.g. birth defects and human infertility.
工作经历

1. State Key Laboratory of Genetic Engineering, 2017-present, Deputy Director

2. Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, 2016-present, Deputy Director

3. Collaborative Innovation Center of Genetics and Development, 2014-present, Deputy Director of Division of Genomics

4. Fudan University, China, 2011-present, Professor/Principal Investigator

5. Fudan University, China, 2009-2011, Associate Professor

6. Baylor College of Medicine, the United States, 2007-2009

7. Postdoctoral Associate; Mentor, Professor James R. Lupski

8. Fudan University, China, 2002-2007

9. Ph.D. in Genetics, July 2007; Mentor, Professor Li Jin

10. East China University of Science and Technology (ECUST), China, 1998-2002

11. Bachelor of Engineering in Biochemical Engineering, June 2002

研究方向
Human genomic rearrangements; copy number variations (CNVs)/structural variations (SVs) and their roles in human diseases, e.g. birth defects and human infertility.
代表论文

1. Wu N*, Ming X*, Xiao J*, Wu Z*, Chen X*, Shinawi M, Shen Y, Yu G, Liu J, Xie H, Gucev ZS, Liu S, Yang N, Al-Kateb H, Chen J, Zhang J, Hauser N, Zhang T, Tasic V, Liu P, Su X, Pan X, Liu C, Wang L, Shen J, Shen J, Chen Y, Zhang T, Zhang J, Choy KW, Wang J, Wang Q, Li S, Zhou W, Guo J, Wang Y, Zhang C, Zhao H, An Y, Zhao Y, Wang J, Liu Z, Zuo Y, Tian Y, Weng X, Sutton VR, Wang H, Ming Y, Kulkarni S, Zhong TP, Giampietro PF, Dunwoodie SL, Cheung SW, Zhang X, Jin L, Lupski JR, Qiu G#, Zhang F# (2015) TBX6 Null Variants and a Common Hypomorphic Allele in Congenital Scoliosis. New England Journal of Medicine 372:341-350.

2. Chen L, Zhou W, Zhang C, Lupski JR, Jin L, Zhang F# (2015) CNV instability associated with DNA replication dynamics: evidence for replicative mechanisms in CNV mutagenesis. Human Molecular Genetics 24(6):1574-1583.

3. Sun Z, Liu P, Jia X, Withers MA, Jin L, Lupski JR, Zhang F# (2013) Replicative mechanisms of CNV formation preferentially occur as intrachromosomal events: evidence from Potocki-Lupski duplication syndrome. Human Molecular Genetics 22(4):749-756.

4. Zhang F, Gu W, Hurles ME, Lupski JR (2009) Copy number variation in human health, disease, and evolution. Annual Review of Genomics and Human Genetics 10:451-481.

5. Zhang F, Khajavi M, Connolly AM, Towne CF, Batish SD, Lupski JR (2009) The DNA replication FoSTeS/MMBIR mechanism can generate human genomic, genic, and exonic complex rearrangements. Nature Genetics 41(7):849-853.

邮箱zhangfeng@fudan.edu.cn
获奖
1. Outstanding Young Scholar, National Natural Science Foundation of China, 2016
2.Outstanding Achievements Award, WuXi PharmaTech Life Science and Chemistry Awards, 2015
3. 2015 Grand Challenges—Young Scientists, Bill & Melinda Gates Foundation, 2015









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